Italy in 10 Days: 4 Recommended 10-day Itineraries to Italy

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Italy 10-day Itinerary Options
A 10-day trip to Italy offers plenty of time to immerse yourself in its rich history and stunning scenery. Check out our Italy 10 days itinerary suggestions to make the most of your journey, from exploring the ancient ruins of Rome to savoring the picturesque canals of Venice and the rolling hills of Tuscany.
Itinerary #1: Mysteries of Northern Italy

Overview | Activity | Overnight | |
Day 1 | Start your trip in Venice. | Arrival | Venice |
Day 2 | Guided boat tour of the Northern Islands; mysteries of Venice nighttime tour in the evening. | Boat ride | Venice |
Day 3 | Morning at leisure then a Cassanova tour in the afternoon. | Exploration | Venice |
Day 4 | Learn more about the Genesis mystery at Belluno. | Historical exploration | Belluno |
Day 5 | Explore Brescia’s medieval castle, lunch and walking tour. | Walking tour | Brescia |
Day 6 | Visit Clusone and enjoy local food and wine at a farm. | Food tour | Clusone |
Day 7 | Tour Milan and discover its secrets with a private tour. | Exploration | Milan |
Day 8 | Visit Turin and the Holy Shroud Museum. | Museum visits | Turin |
Day 9 | Discover Turin’s mysterious alchemical history in a spooky nighttime tour. | Historical exploration | Turin |
Day 10 | Return to Milan and get ready for your next destination. | Departure |
If you're planning to spend 10 days in Italy, this unique tour will guide you through the mysteries of Northern Italy and have you itching to learn more about the region’s history as you come face to face with figures like Casanova and Christ or puzzling over the implications of the Genesis mystery with the scholars who have devoted their lives to it. But don’t worry, just because you’re spending time searching for truth in Italy’s arcane triangle doesn’t mean there won't be time to island hop, explore Italy’s medieval cities, and enjoy some freshly made Italian food! See all 10-day Italy tours.
Itinerary #2: Italy's Famous Cities


Overview | Activity | Overnight | |
Day 1 | Arrive and start to explore Rome. | Arrival | Rome |
Day 2 | Spend the day discovering the mysteries of the Vatican. | Exploring | Rome |
Day 3 | Enjoy Rome’s best sights on a walking tour through the city. | Walking tour | Rome |
Day 4 | Take the train to Florence and explore the city on your own. | Scenic drive | Florence |
Day 5 | Tour Florence’s world-famous architecture via walking tour. | Sightseeing | Florence |
Day 6 | Enjoy a train journey to tour Venice. | Scenic drive | Venice |
Day 7 | Ride a gondola through Venice’s iconic canals. | Exploration | Venice |
Day 8 | Travel to Milan and explore the rich architecture. | Exploration | Milan |
Day 9 | Soak in the city views from the rooftop of the Duomo Cathedral. | City sightseeing | Milan |
Day 10 | Say goodbye to Milan. | Departure |
If you’ve got 10 days in Italy, this itinerary will take you through the greatest hits and sites you don’t want to miss. Start with three days in Rome to take in all the best sights — the Vatican, St. Peter’s Basilica and the Pantheon. After a scenic train ride, you’ll be in Florence, where you can sip Tuscan wine and soak in the artistic and architectural treasures of this Renaissance city. In Venice, ride through the canals on the iconic gondolas before heading to Milan to climb to the top of the Duomo Cathedral for some gorgeous city views. Check out our city sightseeing tours to Italy.
Itinerary #3: Highlights of Southern Italy and Sicily


Overview | Activity | Overnight | |
Day 1 | Rome arrival and city exploration. | Arrival | Rome |
Day 2 | A trip from Rome to the Amalfi Coast, stopping to explore Pompeii and enjoy a traditional lunch before arriving in Salerno | Exploration | Salerni |
Day 3 | Spend a free day in Amalfi (optional excursion to the island of Capri). | Leisure day | Salerni |
Day 4 | Head east to Apulia, explore the ancient cave city of Matera along the way, and end the day in Alberobello, famous for its trulli. | Exploration | Apulia |
Day 5 | Take in the stunning coastal views along the Ionian Sea before crossing over to Sicily for an evening of exploring Taormina and a beachside dinner. | Exploration | Taormina |
Day 6 | Relax on Taormina's beaches or venture to Mount Etna for an adventurous day trip. | Beach activities | Taormina |
Day 7 | Drive through Sicily's stunning landscapes to Syracuse, then continue to the awe-inspiring Valley of the Temples. | Sightseeing | Sicily |
Day 8 | Make your way through central Sicily, taking a break in Cefalù, and then continue towards Palermo. | Exploration | Sicily |
Day 9 | Enjoy a leisurely day in Palermo before boarding an overnight ferry back to the Italian mainland. | Leisure day | Rome |
Day 10 | Journey back to Rome to end your trip. | Departure |
From the eternal allure of Rome to the sun-kissed shores of Palermo, discover the South of Italy in 10 days by embarking on an unforgettable odyssey through its most captivating destinations. Immerse yourself in the ancient wonders of Rome, stroll through the ancient cave city of Matera, explore the ruins of Pompeii, frozen in time since the catastrophic eruption of Mt Vesuvius, and unwind along the scenic Amalfi Coast. Traverse the rugged landscapes of Sicily, from the historical treasures of Taormina and Syracuse to the cultural riches of Palermo, and indulge in local delicacies, such as arancini, cannoli, and sfincione. Conclude your journey with a ferry ride back to Rome.
Itinerary #4: Rome and the Amalfi Coast

Overview | Activity | Overnight | |
Day 1 | Fly overnight to Italy. | Overnight flight | |
Day 2 | Arrive in Rome, and welcome dinner. | Arrival | Rome |
Day 3 | Tour Rome's iconic landmarks, like the Trevi Fountain, the Pantheon, Piazza Navon, and the Colosseum. | City sightseeing | Rome |
Day 4 | Spend a free day in the city, with an optional tour to the Vatican Museums and St. Peter's Basilica, and dinner in Trastevere. | Museum visits | Rome |
Day 5 | Explore the historic Montecassino monastery before heading to the scenic Amalfi Coast. | Scenic drive | Amalfi coast |
Day 6 | Sail along the Amalfi Coast, with stops in the charming coastal towns of Amalfi and Positano. | Boat ride | Amalfi coast |
Day 7 | Discover traditional pasta-making, stroll through Sorrento, and savor fresh mozzarella at a farm-to-table dinner. | Food tour | Amalfi coast |
Day 8 | Savor the Amalfi Coast's tranquility or take a boat trip to Capri for lunch and a guided tour. | Boat ride | Amalfi coast |
Day 9 | Stroll through Pompeii's ruins and savor Lacryma Christi wine before a farewell dinner. | Exploration | Amalfi coast |
Day 10 | Bid goodbye to Italy. | Departure |
Begin your 10-day Italy tour at the heart of Rome, before venturing towards the stunning gems of the Amalfi Coast: Positano and Sorrento. While in the eternal city of Rome, relive the glory of the ancient Roman Empire with an in-depth visit to the Colosseum and the Pantheon, take a stroll to the top of the Spanish Steps for breathtaking views of the city’s skyline, or meander through Rome’s lively Trastevere district to experience an authentic glimpse of the local movida. On day five of your Italy trip, travel to the picturesque Amalfi Coast, with its stunning cliffs and beaches, and discover the culinary delights of Sorrento. Lastly, step back in time amongst the ruins of Pompeii, and enjoy an unforgettable day in Capri to end your 10 days in Italy on a high note. See all Amalfi Coast tours.
Need help planning your 10-day itinerary to Italy?
From the ancient ruins of Rome and the artistic treasure of Florence to the romantic canals of Venice, 10 days in Italy paints a unique picture of its rich history and cultural legacy.
If you plan a customized trip to Italy, contact our travel experts for more Italy 10-day itinerary options. Our article on how many days to spend in Italy and places to visit in Italy will also be helpful while planning your 10-day trip. For a seasonal overview, check out our guide on the best time to visit Italy. Check our articles on 9 days in Italy and 11 days in Italy for information.
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